Table 2.
Properties of nobiletin-loaded vesicular systems.
| Formula code* | Particle size (nm) | PDI | Zeta potential (mV) | EE% | %DL |
|---|---|---|---|---|---|
| F1 | 616.00 ± 11.00 | 0.66 ± 0.19 | − 29.80 ± 9.60 | 60.70 ± 2.60 | 12.14 ± 0.74 |
| F2 | 134.40 ± 15.50 | 0.41 ± 0.07 | − 14.60 ± 2.00 | 65.60 ± 4.60 | 13.12 ± 1.30 |
| F3 | 123.20 ± 1.30 | 0.31 ± 0.06 | − 8.30 ± 1.00 | 67.70 ± 7.70 | 13.54 ± 2.18 |
| F4 | 115.60 ± 7.10 | 0.31 ± 0.06 | − 5.50 ± 3.00 | 71.90 ± 6.40 | 14.38 ± 1.81 |
| F5 | 69.30 ± 1.90 | 0.43 ± 0.07 | − 9.10 ± 0.80 | 74.70 ± 1.60 | 14.94 ± 0.45 |
| F6 | 128.30 ± 7.20 | 0.70 ± 0.14 | − 12.30 ± 1.20 | 67.10 ± 5.20 | 13.41 ± 1.47 |
| F7 | 113.40 ± 5.60 | 0.39 ± 0.02 | − 10.00 ± 0.50 | 66.00 ± 3.80 | 13.19 ± 1.07 |
| F8 | 111.60 ± 20.60 | 0.51 ± 0.10 | − 14.40 ± 5.70 | 64.20 ± 10.00 | 12.83 ± 2.82 |
| F9 | 74.10 ± 7.50 | 0.44 ± 0.20 | − 14.00 ± 0.20 | 54.00 ± 6.90 | 10.78 ± 1.95 |
| F10 | 194.50 ± 31.10 | 0.39 ± 0.01 | + 10.20 ± 3.50 | 89.20 ± 0.80 | 14.39 ± 0.18 |
| F11 | 158.90 ± 0.50 | 0.32 ± 0.05 | + 12.10 ± 1.40 | 94.70 ± 0.20 | 15.28 ± 0.05 |
| F12 | 148.90 ± 15.50 | 0.41 ± 0.04 | + 10.70 ± 1.20 | 95.60 ± 2.80 | 15.42 ± 0.64 |
| F13 | 126.70 ± 11.80 | 0.36 ± 0.00 | + 6.10 ± 0.40 | 93.50 ± 3.60 | 15.08 ± 0.82 |
| F14 | 163.70 ± 4.80 | 0.59 ± 0.01 | + 10.20 ± 0.90 | 94.90 ± 3.00 | 15.31 ± 0.69 |
| F15 | 140.30 ± 10.30 | 0.57 ± 0.01 | + 12.00 ± 1.40 | 96.10 ± 1.40 | 15.49 ± 0.33 |
| F16 | 122.70 ± 10.70 | 0.48 ± 0.13 | + 13.90 ± 2.00 | 95.70 ± 3.30 | 15.42 ± 0.75 |
| F17 | 110.10 ± 0.90 | 0.39 ± 0.01 | + 9.80 ± 2.60 | 95.60 ± 1.50 | 15.40 ± 0.34 |
| F18 | – | – | – | 84.50 ± 2.00 | 12.08 ± 0.40 |
| F19 | – | – | – | 77.70 ± 5.30 | 11.15 ± 1.01 |
| F20 | – | – | – | 83.10 ± 1.20 | 11.87 ± 0.24 |
| F21 | – | – | – | 80.70 ± 1.00 | 11.53 ± 0.19 |
| F22 | – | – | – | 76.80 ± 6.00 | 10.97 ± 1.22 |
| F23 | – | – | – | 82.60 ± 6.20 | 11.79 ± 1.25 |
| F24 | – | – | – | 87.90 ± 0.70 | 12.55 ± 0.14 |
| F25 | – | – | – | 86.30 ± 1.50 | 12.32 ± 0.30 |
| F26 | – | – | – | 87.60 ± 3.70 | 12.50 ± 0.75 |
| F27 | – | – | – | 83.70 ± 4.60 | 10.21 ± 0.79 |
| F28 | – | – | – | 80.60 ± 8.30 | 9.83 ± 1.43 |
| F29 | – | – | – | 80.20 ± 0.30 | 9.78 ± 0.06 |
| F30 | – | – | – | 79.60 ± 6.90 | 9.71 ± 1.19 |
| F31 | – | – | – | 94.80 ± 4.40 | 11.56 ± 0.76 |
| F32 | – | – | – | 93.60 ± 2.30 | 11.41 ± 0.39 |
| F33 | – | – | – | 95.00 ± 1.30 | 11.58 ± 0.23 |
| F34 | – | – | – | 95.40 ± 1.30 | 11.62 ± 0.23 |
*The particle size of cerosomes (F18–F34) was not determined owing to the fact that cerosomes are not spherical vesicles but have tubular like morphology.