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IC50 values of nobiletin solution, composite PEVs (F13) and composite transfersomes (F17) on A431 cell line after 24 and 48 h (n = 3).
| Time (h) | IC50 (µg/ml) | ||
|---|---|---|---|
| Nobiletin solution | Nobiletin-loaded composite PEVs (F13) | Nobiletin- loaded composite transfersomes (F17) | |
| 24 | 61.70 ± 2.10 | 87.10 ± 3.70 | 107.00 ± 7.20 |
| 48 | 46.70 ± 1.40 | 16.70 ± 0.94 | 30.90 ± 1.50 |
