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. 2021 Oct 12;12:5955. doi: 10.1038/s41467-021-25860-5

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a–c Mean module score for IFN-γ response within samples over time points for lymphoid (a), myeloid (b), tumor cells (c). Samples from a single patient are connected with a dashed line. The size of markers is proportional to the number of relevant cells in a sample; only samples with more than 5 cells of the corresponding type are considered. Points at 0 days relative to ICI administration are pre-treatment. d Violin plots of IFN-γ response for tumor cells plotted against survival (time-on-trial), for samples taken <30 days after initial ICI administration. Medians and upper and lower quartiles are indicated in each violin plot by dashed lines.