Table 3.
Cumulative Acute and Late Toxicities, Feeding Tube Requirement
| All Patients (n=137) | Mucosa SBRT Site (n=55) | Non-Mucosa SBRT Site (n=82) | p-value | Concurrent Chemotherapy (n=96) | No Concurrent Chemotherapy (n=41) | p-value | |
|---|---|---|---|---|---|---|---|
| Any Grade 2+ Toxicity | 42 (31%) | 27 (49%) | 15 (18%) | 0.001 | 36 (38%) | 6 (15%) | 0.01 |
| Any Grade 3+ Toxicity | 21 (15%) | 16 (29%) | 5 (6%) | 0.001 | 19 (20%) | 2 (5%) | 0.02 |
| Feeding Tube Requireda | 22 (21%) | 17 (38%) | 5 (8%) | <0.001 | 18 (25%) | 4 (11%) | 0.07 |
Excludes n=23 patients who had feeding tube placed prior to SBRT and n=7 patients who had feeding tube placed for other confirmed cause (i.e. surgery, frank tumor progression)
Abbreviations: SBRT, stereotactic body radiotherapy