Table 4.

Summary table of large series examining the “Weekend Effect” in endovascular thrombectomy for acute ischemic stroke.

Author/Year	Number of Sites	Number of Patients	Hospital Setting	Statistical Model Adjustment	Weekend Effect Detected
Almetkhlafi et al. 2014 (9)	1	110	Academic	No mention/No difference in NIHSS	Increased imaging-to-reperfusion time
Saad et al. 2014 (6)	Multicenter national database (NIS 2005–2011)	12,055	Academic and community	Stepwise logistic regression model/No control for NIHSS	Patients admitted to nonteaching hospitals more likely to have moderate-to-severe disability
Mpotsaris et al. 2015 (10)	1	98	Academic	No mention/No difference in NIHSS	Prolongation of door-to-needle time
Nikoubashman et al. 2017 (26)	1	358	Academic	No mention/No difference in NIHSS	None
Raymond et al. 2018 (11)	1	129	Academic	No mention/No difference in NIHSS	None
Zaeske et al. 2020 (8)	1	246	Academic	No mention/No difference in NIHSS	Increased in-hospital mortality
Dandapat et al. 2020 (12)	1	315	Academic	Ordinal/logistical regression models/No difference in NIHSS	None
Weddell et al. 2020 (13)	1	501†	Academic	Model controlled for baseline demographic and clinical characteristics/No difference in NIHSS	Door-to-imaging, door-to-groin times significantly longer, thrombectomy duration shorter
Tschoe et al. 2020 (15)	6 centers (multicenter STAR registry database*)	1919	Academic	Multivariable ordinal logistic regression model/No difference in NIHSS	None
Potts et al. 2021 (26)	1	216	Academic	No mention/No difference in NIHSS	Increased door-to-groin puncture time
Current study	Multicenter national database (NIS 2016–2018)	6052	Academic and community	Mixed-effects logistic regression model/Controlled for NIHSS, no difference in NIHSS	None

^*Prospective, observational database in the United States

^†Study reported number of procedures rather than number of patients.

NIHSS, National Institutes of Health Stroke Scale; STAR, Stroke Thrombectomy and Aneurysm Registry; NIS, National (Nationwide) Inpatient Sample