Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 12;6:120. doi: 10.1038/s41541-021-00383-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Groups of mice (n = 6) were immunized with 10 µg of Pro-6C constructs with alum. Day-56 serum was tested for antibody reactivity on ELISA plates coated with Pfs48/45-6C (a) and Pfs230-Pro (b). Antibody titers (dots represent individual mice) are expressed as EC50 values. Horizontal lines represent median values. c Functional activity of pooled sera (1:9 and 1:27 dilution) in the standard membrane-feeding assay (SMFA). Reported values and 95% confidence intervals (bars) are determined by general linearized mixed models and used oocyst-count data from two independent SMFA experiments with 20 mosquitoes per condition and experiment. Transmission-reducing activity is calculated by comparing with a nonserum control included in each SMFA.