Table 1.

Mass Balance summary of ProC6C.

Step	1 L Total protein (mg/L)	1 L ProC6C (mg/L)	5 L Total protein (mg/L)	5 L ProC6C (mg/L)
Harvest supernatant	22300a	30–35	22800a	30–40
Diafiltration/buffer exchange	680	30–35	645	38
Capture (Q)	390	25–27b	360	26–30b
HCP removal (Capture select)	40	18–22b	35	18–22b
Polishing (Q)	15	12–15c	12	10–12c

^aTotal protein is over-estimated due to the presence of Cysteine and Cystine in the medium.

^bAmount of ProC6C in the eluate.

^cAmount of ProC6C monomer in the eluate.