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. 2021 Oct 12;11:20192. doi: 10.1038/s41598-021-99717-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Spectral power density differentiates epilepsy from other brain disorders. (A) First latent variable (p < 0.001; 50.1% cross-block covariance) (B) second latent variable (p < 0.001; 29.9% cross-block covariance), and (C) third latent variable (p = 0.068; 10.1% cross-block covariance) of a PLS analysis relating clinical data to SPD. Left panels: correlation coefficients; middle panels: bootstrap ratios; right panels: average (± SEM) SPD, with subjects split into two groups according to their LV-scores. SPD functions were first averaged across electrodes within subjects, then averaged across subjects within each group. Figure panels created in MATLAB v.9.1 and merged using Adobe Illustrator CS6.