Table 4.

Hazard ratios of sudden sensorineural hearing loss or Meniere’s disease by age between patients with and without chronic kidney disease.

Variables	N	Case	Person–years	Incidence	Unadjusted HR (95% CI)	P value	Adjusted HR (95% CI)	P value
SSNHL
Age (years) < 45
Comparison group	1408	8	6948.9	0.51	1 (ref)		1 (ref)
CKD group	709	8	15,834.1	1.15	2.08 (0.78–5.54)	0.143	2.05 (0.77–5.48)	0.152
Age (years) 45–64
Comparison group	2409	17	27,034.5	0.63	1 (ref)		1 (ref)
CKD group	1197	17	10,754.8	1.58	2.27 (1.16–4.45)*	0.017	2.36 (1.20–4.62)*	0.012
Age (years) > 64
Comparison group	1327	9	13,691.3	0.66	1 (ref)		1 (ref)
CKD group	666	6	4652.1	1.29	1.82 (0.64–5.11)	0.259	1.92 (0.68–5.42)	0.220
Meniere’s Diseases
Age (years) < 45
Comparison group	1408	28	15,850.1	1.77	1 (ref)		1 (ref)
CKD group	709	13	6944.2	1.87	1.21 (0.62–2.36)	0.572	1.22 (0.63–2.38)	0.561
Age (years) 45–64
Comparison group	2409	98	26,914.0	3.61	1 (ref)		1 (ref)
CKD group	1197	45	10,718.3	4.20	1.48 (1.03–2.12)*	0.033	1.50 (1.04–2.14)*	0.029
Age (years) > 64
Comparison group	1327	64	13,408.6	4.77	1 (ref)		1 (ref)
CKD group	666	23	4618.1	4.98	1.46 (0.90–2.37)	0.130	1.50 (0.92–2.45)	0.102

SSNHL, Sudden sensorineural hearing loss; CKD, Chronic kidney disease; CI, Confidence interval (*P < 0.05).