Table 3.
Additive calibration, discrimination, and reclassification value of ePWV on 4C mortality score for predicting 28-day mortality (n = 626).
| Discrimination | Reclassification | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AIC | Likelihood ratio chi-squared | P value | AUC (95% CI) |
ΔAUC (95% CI) |
P value | IDI (95% CI) |
P value | Event subjects (%) | Non-event subjects (%) | Overall NRI (95% CI) | P value | |
| 4C mortality score | 524.2 | 8.96 | 0.003 |
0.779 (0.743–0.818) |
0.038 (0.028–0.054) |
< 0.001 |
1.2 (0.1–3.6) |
0.006 | 8.7 | 29.4 |
0.381 (0.144–0.568) |
< 0.001 |
| ePWV | 517.2 |
0.817 (0.780–0.850) |
||||||||||
| Charlson comorbidity index | 727.1 | 77.5 | < 0.001 |
0.692 (0.649–0.728) |
0.077 (0.058–0.112) |
< 0.001 |
4.5 (1.5–8.5) |
< 0.001 | 17 | 37.8 |
0.548 (0.015–0.85) |
< 0.001 |
| ePWV | 651.5 |
0.769 (0.732–0.801) |
||||||||||
95% CI are derived from bootstrapping with 1,000 replicates.
4C, Coronavirus Clinical Characterisation Consortium; ePWV, estimated pulse wave velocity; AIC, Akaike information criterion; AUC, area under the curve; NRI, net reclassification index; ΔAUC, difference in AUC; IDI, integrative discrimination index; NRI, net reclassification improvement.