. 2021 Oct 12;4:1181. doi: 10.1038/s42003-021-02714-w

Table 2.

Capture and detection of LAM from the urine of subjects with pulmonary TB by Sandwich ELISA.

Diagnosis^a	Microbiology		U-LAM^b ELISA OD₄₅₀		U-LAM Detection^c	GC-MS (ng/mL)^d
	Smear^e	Culture^f	CS35/A194	L1AM04/T1AM09
Pulmonary TB	pos	Mtb	1.649	1.531	Positive	25
Pulmonary TB	pos	Mtb	0.894	0.627	Positive	14.3
COPD, Pneumonia	neg	neg	0.233	0.210	Negative	Not detected
Pneumonia, TB unlikely	neg	neg	0.196	0.221	Negative	Not detected

^aAll four patients were HIV uninfected.

^bCapture ELISA for the detection of LAM in urine (U-LAM).

^cU-LAM detection above cut-off based on background values for healthy control urine for each mAb pair by capture ELISA (OD450 0.259 for CS35/A194 mAb pair and 0.335 for L1AM04/T1AM09 mAb pair, respectively).

^dQuantification of U-LAM by gas chromatography-mass spectrometry (GS-MS) D-Arabinose detection method.

^eSputum smear microscopy for acid fast bacilli (AFB).

^fMycobacterial culture of sputum.