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. 2021 Oct 12;10(10):68. doi: 10.1038/s41389-021-00357-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A ATP viability assays at 48 and 96 h of treatment of NCC-CDS-X1 cells with different concentrations of iP300w stereoisomers and A-485. B IC₅₀ values of A-485, Comp 13 and iP300w in NCC-CDS-X1 cells at 48 and 98 h of treatment. C RT-qPCR for CIC-DUX4 target genes in NCC-CDS-X1 cells after 24 h treatment with 0.03 and 0.3 µM iP300w stereoisomers and A-485. Data is presented as mean ± SEM; *p < 0.05, by two-way ANOVA. Results are presented as expression relative to control (n = 3).