Table 2.
Comparison of demographic data, comorbid conditions, and disease-specific variables between atopic and non-atopic CRS patients.
| Variables | Atopic CRS (n=286) n (%) |
Non-atopic CRS (n=94) n (%) |
P-value |
|---|---|---|---|
| Age | 49.4 ± 15.6years | 56.4 ± 17.1years | <0.0001 |
| Sex | |||
| Male | 125 (43.7%) | 50 (53.2%) | 0.087 |
| Female | 161 (56.3%) | 44 (46.8%) | |
| Race | |||
| Caucasian | 174 (60.8%) | 57 (60.7%) | 0.370 |
| Black | 53 (18.5%) | 15 (16.0%) | |
| Latino | 26 (9.2%) | 14 (14.9%) | |
| Asian | 11 (3.8%) | 4 (4.3%) | |
| Other | 22 (7.7%) | 4 (4.3%) | |
| Smoking status | |||
| Never | 188 (65.7%) | 60 (63.8%) | 0.436 |
| Past | 78 (27.3%) | 24 (25.5%) | |
| Current | 20 (7.0%) | 10 (10.7%) | |
| Polypoid disease | 162 (56.3%) | 33 (35.9%) | 0.001 |
| Comorbid asthma | 128 (44.8%) | 16 (17.0%) | <0.0001 |
| Comorbid AERD | 27 (9.4%) | 1 (1.1%) | 0.003 |
| Comorbid GERD | 76 (26.6%) | 34 (36.2%) | 0.075 |
| Elevated total serum IgE (>200 kilounits (kU) /L) | 31/93* (33.3%) | 1/12* (8.3%) | 0.032 |
| Allergen sensitization | |||
| Mono (1) | 68 (23.8%) | n/a | n/a |
| Poly (2+) | 218 (76.2%) |
*
Total serum IgE levels were only available in a subset of patients (n=105): 93 atopic CRS and 12 non-atopic CRS.