Fig. 7.

TrkC alternative splicing returns to baseline in 7 weeks post TBI.

7 weeks post injury, total RNA was isolated from cortex of mice with sham injury, TBI, TBI treated with hASC exosomes (TBI+EXO) or TBI treated with MALAT1 depleted hASC exosomes (TBI+EXO-M); n = 5 in each group. SYBR Green qPCR was performed in triplicate with primers specific for TrkC_FL, TrkC_T1 or IL1β and β-actin as internal control. The graph shows relative quantification (RQ) with sham (no TBI) set as reference. Statistical analysis was performed using Tukey’s multiple comparisons test; ns = not significant.