TABLE 5.
Exposure | Mean rev/ml-eq | Fold increase | Reference |
---|---|---|---|
Smoky coal combustion emissions | 24.8 | 31.5 | Present study |
Diesel engine exhaust | 19.6 | 3.5 | Present study |
Benzidine | 496.0 | 20.7 | DeMarini et al. (1997) |
Charcoal production emissions | 276.0 | 2.3 | Kato et al. (2004) |
Nitrotoluenes | 127.0 | Not reported | Sabbioni et al. (2006) |
Wildfire | 11.0 | 2.6 | Wu et al. (2021) |
Other than for benzidine, all other data were generated in Salmonella frameshift strain YG1041, which over-expresses both O-acetyltransferase and nitroreductase. The benzidine data were generated in the related strain YG1024, which over-expresses only O-acetyltransferase. Data for benzidine were extrapolated from published dose-response curves, and data for charcoal emissions were estimated from published data.