Table 2. Antimicrobial resistance levels of Enterococcus faecium and Staphylococcus aureus isolates.
A) Enterococcus faecium | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | PEN | AMP | VAN | GENa | STRa | TET | CIP | RIF | ||||||||||||
% | P | % | P | % | P | % | P | % | P | % | P | % | P | % | P | |||||
M+S+I | P1 | 194 | 90 | NS | 90 | NS | 42 | <0.05 | 74 | NS | 67 | NS | 56 | NS | 93 | NS | 88 | <0.05 | ||
P2 | 255 | 93 | 91 | 53 | 74 | 68 | 63 | 95 | 78 | |||||||||||
O | 449 | 91 | 90 | 48 | 74 | 67 | 60 | 94 | 82 | |||||||||||
M | P1 | 119 | 93 | NS | 92 | NS | 36 | <0.05 | 80 | NS | 67 | NS | 60 | NS | 96 | NS | 86 | NS | ||
P2 | 153 | 95 | 93 | 52 | 76 | 72 | 65 | 95 | 79 | |||||||||||
O | 272 | 94 | 92 | 45 | 78 | 70 | 62 | 95 | 82 | |||||||||||
S | P1 | 40 | 90 | NS | 90 | NS | 47 | NS | 72 | NS | 75 | NS | 47 | NS | 95 | NS | 95 | <0.05 | ||
P2 | 71 | 89 | 88 | 46 | 71 | 60 | 59 | 94 | 77 | |||||||||||
O | 111 | 89 | 89 | 46 | 71 | 66 | 55 | 94 | 84 | |||||||||||
I | P1 | 35 | 80 | NS | 80 | NS | 54 | NS | 54 | NS | 57 | NS | 49 | NS | 93 | NS | 86 | NS | ||
P2 | 31 | 94 | 90 | 74 | 71 | 71 | 58 | 97 | 74 | |||||||||||
O | 66 | 86 | 85 | 64 | 62 | 64 | 53 | 95 | 80 | |||||||||||
P1 | PM+S/I | 0.06 | 0.07 | NS | <0.05 | NS | NS | NS | NS | |||||||||||
P2 | PM+S/I | NS | NS | NS | NS | NS | NS | NS | NS | |||||||||||
O | PM+S/I | NS | NS | <0.05 | <0.05 | NS | NS | NS | NS |
aHigh level resistance.
In the Table are only reported significant differences (P <0.05), as well as those P-values ≤0.09.
In addition, susceptibility to linezolid was tested in 39 E. faecium and 53 S. aureus isolates from Period 2 with all being susceptible.
All S. aureus isolates were susceptible to vancomycin. In addition, chloramphenicol was tested in S. aureus from Period 1 showing an overall resistance rate of 16% with a maximum among intensive care unit isolates of 21%.
M, medicine; S, surgery; I, intensive care unit; P1, Period 1 (2009 - 2010); P2, Period 2 (2012 - 2014); O, overall; PEN, penicillin; AMP, ampicillin; VAN, vancomycin; GEN, gentamicin; STR, streptomycin; TET, tetracycline; CIP, ciprofloxacin; RIF, rifampicin; NS, non significant; OXA, oxacillin; ERY, erythromycin; CLI, clindamycin; TMP/SMX, trimethoprim-sulfamethoxazole.