Table 4. Antimicrobial resistance levels of Acinetobacter baumannii and Pseudomonas aeruginosa isolates.
A) Acinetobacter baumannii | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Antibiotic resistance levels | |||||||||||||||||||||
SAM | CTX | CAZ | FEP | IPM | MEM | AMK | GEN | CIP | TMP/SMX | |||||||||||||
% | P | % | P | % | P | % | P | % | P | % | P | % | P | % | P | % | P | % | P | |||
M+S+I | P1 | 189 | 65 | <0.05 | 91 | 0.06 | 85 | <0.05 | 85 | <0.05 | 63 | <0.05 | 61 | <0.05 | 84 | <0.05 | 78 | NS | 89 | NS | 86 | NS |
P2 | 414 | 91 | 97 | 93 | 93 | 90 | 88 | 69 | 72 | 93 | 90 | |||||||||||
O | 603 | 83 | 95 | 91 | 91 | 81 | 80 | 74 | 74 | 92 | 89 | |||||||||||
M | P1 | 100 | 61 | <0.05 | 87 | NS | 81 | NS | 81 | NS | 61 | <0.05 | 61 | <0.05 | 81 | <0.05 | 78 | NS | 87 | NS | 84 | NS |
P2 | 147 | 89 | 92 | 88 | 88 | 86 | 78 | 59 | 71 | 88 | 84 | |||||||||||
O | 247 | 78 | 90 | 85 | 85 | 76 | 72 | 68 | 74 | 88 | 84 | |||||||||||
S | P1 | 33 | 68 | <0.05 | 88 | NS | 82 | <0.05 | 82 | 0.08 | 63 | <0.05 | 64 | <0.05 | 82 | NS | 73 | NS | 88 | NS | 91 | NS |
P2 | 94 | 91 | 95 | 94 | 93 | 87 | 90 | 67 | 76 | 94 | 89 | |||||||||||
O | 127 | 86 | 93 | 91 | 90 | 81 | 83 | 71 | 75 | 93 | 90 | |||||||||||
I | P1 | 56 | 61 | <0.05 | 100 | NS | 95 | NS | 93 | NS | 67 | <0.05 | 71 | <0.05 | 91 | <0.05 | 80 | <0.05 | 93 | NS | 86 | <0.05 |
P2 | 173 | 91 | 99 | 96 | 98 | 95 | 95 | 74 | 72 | 97 | 96 | |||||||||||
O | 229 | 83 | 99 | 96 | 97 | 88 | 89 | 78 | 76 | 95 | 93 | |||||||||||
P1 | PM+S/I | NS | <0.05 | <0.05 | <0.05 | NS | NS | NS | NS | NS | NS | |||||||||||
P2 | PM+S/I | NS | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 | NS | <0.05 | <0.05 | |||||||||||
O | PM+S/I | NS | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 | NS | <0.05 | <0.05 |
In the Table are only reported significant differences (P <0.05), as well as those P-values ≤0.09.
In Period 2 susceptibility to colistin was established in 20 A. baummanni and 31 P. aeruginosa isolates, and that of tigecycline was established in 37 A. baumanni isolates, all being susceptible.
M, medicine; S, surgery; I, intensive care unit; P1, Period 1 (2009 - 2010); P2, Period 2 (2012 - 2014); O, overall; SAM, ampicillin-sulbactam; CTX, cefotaxime; CAZ, ceftazidime; FEP, cefepime; IPM, imipenem; MEM, meropenem; AMK, amikacin; GEN, gentamicin; CIP: ciprofloxacin; TMP/SMX, trimethoprim-sulfamethoxazole; NS, non significant; ATM, aztreonam; TZP, piperacillin-tazobactam.