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. 2020 Aug 10;53(3):578–581. doi: 10.3947/ic.2020.0045

Table 1. Serial changes in viral load observed for a patient with COVID-19.

HD 3 HD 6 HD 8 HD 10 HD 13 HD 15 HD 17 HD 20 HD 21 HD 27
Pharyngeal swab + + + +
RdRP assay (Ct cutoff of 40) 36.98 28.91 UD UD 32.85 UD 32 UD UD
Sputum + + + + + + +
RdRP assay (Ct cutoff of 35) 27.23 25.42 26.44 22.36 31.2 28.66 31.79 UD
Pleural fluid +
RdRP assay (Ct cutoff of 35) 34.51 UD

COVID-19 was confirmed by RT-PCR: pharyngeal swab for Allplex 2019-nCoV Assay (Seegene, Inc, Seoul, Korea) and sputum and pleural fluid samples for PowerChek SARS-CoV-2 Real-time PCR Kit (KogeneBiotech, Seoul, Korea), respectively.

COVID-19, coronavirus disease 2019; HD, hospital day; RdRP, RNA-dependent RNA polymerase; Ct, cycle threshold; +, positive; −, negative; UD, undetected; RT-PCR polymerase chain reaction; SARS-CoV-2, syndrome coronavirus 2.