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Kinetic parameters of rMgTx and Kv channel interaction.
| Kv Channel | Toxin | k on (pM−1s−1) | k off (sec−1) | K d (pM) |
|---|---|---|---|---|
| Kv1.3 | TrMgTx | 2.14E-05 | 0.00179 | 83.90 |
| UrMgTx | 3.43E-05 | 0.00179 | 52.20 | |
| Kv1.2 | TrMgTx | 3.05E-05 | 0.00190 | 62.29 |
| UrMgTx | 4.62E-05 | 0.00098 | 15.04 |
k on and k off were calculated from averaged τ on and τ off values obtained from 3–5 independent experiments (see the Materials and Methods section for details). K d was determined as k off /k on .
