TABLE 1.

Effects of the CEF and Aβ25–35 administration (AD model) on the behavior of mice in the open field test.

Index	Group				Effects (F, p)
	H2O + saline	H2O + CEF	Aβ25–35 + saline	Aβ25–35 + CEF
Locomotor activity (path length, cm)	2728.0 ± 106.2	3224.7 ± 223.2*	2668.2 ± 157.9	2580.5 ± 184.9$	Aβ: F(1,37) = 4.4, p < 0.05; CEF: F(1,37) = 1.5, p > 0.05; Aβ × CEF: F(1,37) = 3.0, p > 0.05
Exploratory activity (no. of rearings)	65.9 ± 3.9	63.5 ± 5.5	60.1 ± 5.3	58.4 ± 7.0	Aβ: F(1,37) < 1; CEF: F(1,37) < 1; Aβ × CEF: F(1,37) < 1
Anxiety (time in the center, s)	31.8 ± 4.1	34.1 ± 7.7	26.9 ± 3.7	21.9 ± 2.7	Aβ: F(1,37) = 3.1, p > 0.05; CEF: F(1,37) < 1; Aβ × CEF: F(1,37) < 1
Emotionality (no. of fecal boluses)	1.40 ± 0.48	1.17 ± 0.65	2.08 ± 0.59	2.14 ± 0.51	Aβ: F(1,37) = 1.8, p > 0.05; CEF: F(1,37) < 1; Aβ × CEF: F(1,37) < 1

Data are presented as mean ± SEM of the values obtained in an independent group of animals (n = 7–15 per group). Statistically significant differences: *p < 0.05 vs. the “H₂O + saline” group; $ p < 0.05 vs. the “H₂O + CEF” group.