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. 2021 Sep 29;15:742198. doi: 10.3389/fnhum.2021.742198

TABLE 2.

General linear models with all covariates (T1 DTI predicting T2 total CAPS symptoms).

Left hemisphere
Right hemisphere
β CI p β CI p
Uncinate fasciculus Intercept −11.31 −30.80 – 8.18 0.25 −4.31 −28.94 – 20.32 0.73
FA 42.36 3.74 – 80.99 0.03# 19.75 −30.15 – 69.64 0.43
Age −0.08 −0.26 – 0.10 0.38 −0.07 −0.26 – 0.11 0.42
Sex 0.64 −3.09 – 4.38 0.73 0.31 −3.55 – 4.16 0.87
T1 PCL-5 0.24 0.13 – 0.35 <0.001* 0.25 0.14 – 0.37 <0.001*
T1 LEC 0.05 −0.07 – 0.16 0.42 0.02 −0.10 – 0.14 0.75
T1 translation 6.17 −0.17 – 12.50 0.05 5.22 −1.24 – 11.68 0.11
T1 rotation −1156.31 −2073.85 − –238.77 0.01# −684.20 −1834.97 – 466.56 0.24
Anterior cingulum Intercept 33.51 8.07 – 58.95 0.01 23.09 −1.27 – 47.45 0.06
FA −53.28 −94.69 −−11.87 0.01# −35.88 −76.90 – 5.14 0.08
Age −0.06 −0.22 – 0.11 0.49 −0.06 −0.23 – 0.10 0.46
Sex −0.99 −4.52 – 2.54 0.58 −0.73 −4.31 – 2.85 0.68
T1 PCL-5 0.25 0.14 – 0.36 <0.001* 0.24 0.13 – 0.35 <0.001*
T1 LEC 0.01 −0.10 – 0.12 0.87 0.02 −0.09 – 0.13 0.65
T1 translation 4.34 −1.63 – 10.32 0.15 4.93 −1.11 – 10.98 0.11
T1 rotation −771.95 −1607.28 – 63.37 0.07 −812.71 −1659.03 – 33.61 0.066
Posterior cingulum Intercept −5.57 −27.34 – 16.19 0.61 −3.32 −28.27 – 21.64 0.79
FA 16.07 −31.67 – 63.81 0.51 16.37 −34.76 – 67.49 0.53
Age −0.01 −0.20 – 0.19 0.94 −0.01 −0.23 – 0.22 0.94
Sex 0.01 −4.07 – 4.10 0.99 −1.41 −6.02 – 3.20 0.55
T1 PCL-5 0.24 0.12 – 0.37 <0.001* 0.26 0.13 – 0.39 <0.001*
T1 LEC 0.08 −0.05 – 0.20 0.22 0.04 −0.10 – 0.18 0.57
T1 translation 5.55 −1.92 – 13.01 0.14 6.21 −1.35 – 13.77 0.11
T1 rotation −764.99 −1991.61 – 461.63 0.22 −904.55 −2214.89 – 405.79 0.17
Forceps minor Intercept 8.99 −12.93 – 30.90 0.42
FA −9.43 −49.51 – 30.66 0.64
Age −0.03 −0.20 – 0.14 0.75
Sex −0.64 −4.26 – 2.98 0.73
T1 PCL-5 0.23 0.12 – 0.34 <0.001*
T1 LEC −0.00 −0.11 – 0.11 0.99
T1 translation 4.49 −1.72 – 10.71 0.15
T1 rotation −760.61 −1618.91 – 97.69 0.08
Forceps major Intercept −0.52 −28.45 – 27.42 0.97
FA 10.21 −31.06 – 51.49 0.62
Age −0.08 −0.29 – 0.13 0.47
Sex 0.27 −3.98 – 4.51 0.90
T1 PCL-5 0.21 0.08 – 0.33 0.002*
T1 LEC 0.05 −0.08 – 0.19 0.44
T1 translation 6.07 −1.08 – 13.23 0.09
T1 rotation −1063.73 −2030.91 – −96.55 0.03

T1, 2-weeks post-trauma; T2, 6-months post-trauma; CAPS, Clinician Administered PTSD Scale; LEC, life events checklist total weighted score; FA, fractional anisotropy. p-values presented are uncorrected, bolded values with * indicates results that survived Benjamini–Hochberg correction (α = 0.05). # indicates marginal results after correction (p adjusted < 0.10).