Table 2.
Peripheral nerve data.
| Sciatic nerve | Tibial nerve | Fibular nerve | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HC – ANNI | HC – ANINJ | AN NI – AN INJ | HC – ANNI | HC – ANINJ | AN NI – AN INJ | HC – ANNI | HC – ANINJ | AN NI – AN INJ | ||
| Diffusion tensor imaging | ||||||||||
| FA_M | AD | −0.06 ** | −0.029 | 0.029*** | −0.003 | 0.044 | 0.063* | 0.008 | 0.037 | 0.029 |
| (CI) | (−0.1, −0.02) | (−0.072, 0.015) | (0.014, 0.044) | (−0.054, 0.047) | (−0.039, 0.126) | (0.021, 0.104) | (−0.052, 0.068) | (−0.026, 0.099) | (−0.001, 0.059) | |
| FA_SD | AD | −0.009 | 0.005 | 0.009** | −0.009 | 0.014 | 0.019* | −0.008 | 0.015 | 0.023* |
| (CI) | (−0.024, 0.006) | (−0.008, 0.018) | (0.002, 0.015) | (−0.032, 0.015) | (−0.023, 0.052) | (0.001, 0.037) | (−0.039, 0.022) | (−0.021, 0.05) | (0.009, 0.039) | |
| RD_M | AD | 3.53 | 1.02 | −2.22*** | −2.36 | −9.3*** | −4.13* | −6.13*** | −6.44*** | 0.92 |
| (CI) | (−0.64, 7.69) | (−3.42, 5.45) | (−3.29, −1.15) | (−6.12, 1.4) | (−13.3, −5.2) | (−7.28, −0.96) | (−8.77, −3.49) | (−9.49, −3.4) | (−1.55, 3.4) | |
| RD_SD | AD | −50.8 | −52.5 | −0.7 | −1.53 | −1.17 | −1.04 | −12.7 | −9.97 | 1.87 * |
| (CI) | (−126.6, 25) | (−130.6, 25.6) | (−1.44, 0.03) | (−4.58, 1.53) | (−5.67, 3.33) | (−2.6, 0.52) | (−29.9, 4.57) | (−31.5, 11.6) | (0.47, 3.27) | |
| AD_M | AD | 0.014 | −2.9 | −3.14*** | −2.6 | −13*** | −4.99* | −9.1*** | −7.91*** | 2.84 |
| (CI) | (−8.25, 8.28) | (−11.7, 5.9) | (−4.57, −1.72) | (−14.1, 8.92) | (−18.5, −7.5) | (−9.37, −0.62) | (−12.6, −5.6) | (−12.05, −3.78) | (−0.27, 5.6) | |
| AD_SD | AD | −91.4 | −84.2 | 0.05 | −3.13 | −3.26 | −2.32* | −146 | −179 | 2.82*** |
| (CI) | (−226, 43.8) | (−220.5, 52) | (−0.77, 0.87) | (−7.06, 0.81) | (−8.64, 2.12) | (−4.44, −0.2) | (−448, 156) | (−553, 194) | (1.11, 4.53) | |
| MD_M | AD | 2.65 | −0.26 | −2.55*** | −7.89*** | −11.0*** | −4.52* | −6.9*** | −6.72*** | 1.41 |
| (CI) | (−2.94, 8.24) | (−6.23, 5.7) | (−3.73, −1.37) | (−10.4, −5.39) | (−15.5, −6.5) | (−7.96, −1.08) | (−9.8, −4) | (−10.08, −3.37) | (−1.21, 4.03) | |
| MD_SD | AD | −0.43 | −0.43 | −0.47 | −1.9 | −1.65 | −1.46 | −101 | −125 | 2.2** |
| (CI) | (−3.05, 2.2) | (−2.8, 1.93) | (−1.21, 0.27) | (−5.11, 1.31) | (−6.22, 2.91) | (−3.1, 0.19) | (−315, 112) | (−390, 140) | (0.73, 3.68) | |
| Magnetization transfer ratio | ||||||||||
| MTR_M | AD | 0.008 | −0.24 | −0.58 | 1.26 | 0.69 | −0.67 | 1.67 | 0.31 | −1.63* |
| (CI) | (−3.03, 3.04) | (−2.98, 2.5) | (−1.28, 0.11) | (−1.27, 3.78) | (−1.42, 2.81) | (−1.88, 0.54) | (−2.01, 5.34) | (−4.02, 4.63) | (−3.14, −0.13) | |
| MTR_SD | AD | 0.019 | −0.03 | 0.21 | −0.34 | −0.34 | −1.0* | −1.52 | −0.89 | −0.09 |
| (CI) | (−2.24, 2.28) | (−2.38, 2.31) | (−0.24, 0.66) | (−2.75, 2.08) | (−2.9, 2.23) | (−1.84, −0.16) | (−3.54, 0.5) | (−2.06, 1.27) | (−0.95, 0.78) | |
M, mean values within imaging slices and SD reflects standard deviation within a slice. Groups are compared based on diffusion tensor imaging and magnetization transfer ratio imaging with adjusted difference values reported.
*
p < 0.05,
**
p < 0.005,
***
p < 0.001.
HC, Healthy Control; ANNI, Ankle No Injury; ANINJ, Ankle Injury.