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. 2021 Jun 18;105(4):827–836. doi: 10.1093/biolre/ioab119

Table 4.

Combined effect of CLOCK and CRY2 (median splits) on sPTB in 2nd trimester maternal blood (n = 51 sPTB, n = 106 term) with logistic regression model.

N (%) Term, n (%) sPTB, n (%) ORsPTB vs term (95% CI) P
High risk level* 40 (100.0) 20 (50.0) 20 (50.0) 4.86 (1.75, 13.51) 0.0025
Middle risk level*** 76 (100.0) 52 (68.4) 24 (31.6) 2.24 (0.87, 5.78) 0.0946
Low risk level** 41 (100.0) 34 (32.1) 7 (13.7) Ref.

*Both CLOCK and CRY2 transcripts ≤ median.

**Both CLOCK and CRY2 transcripts > median.

***All other combinations.