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. 2021 Sep 29;8:701745. doi: 10.3389/fcvm.2021.701745

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Copyright © 2021 Chen, Gao, Wu, Wang, Sun, Jiang, Guo, Guo, Liu, Chen, Liu, Wang, Zhang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glycolysis increased in human fibrotic heart tissues compared with the non-fibrotic heart tissues. (A) Masson staining of the human fibrotic and non-fibrotic heart tissues. The representative image (left) and the statistical analysis (right) were shown. (B) Immunofluorescence of the human fibrotic and non-fibrotic heart tissues. The green fluorescence signal represented α-SMA, and the blue fluorescence signal represented DAPI. (C) Western blot of the expressions of glycolytic and CF activation markers of the human fibrotic and non-fibrotic heart tissues. The representative image (left) and the statistical analysis (right) were shown, respectively. N = 3; *P < 0.05; **P < 0.01; ns, no significance. Scale bar = 100 μm.