Table 2.

Brain endothelial transcripts.

Gene symbol	Gene title	Fold change Ctnnb1OE−EC > Ctnnb1WT	Adjusted p-value for Diff of genotype = Ctnnb1 OE −EC –Ctnnb1 WT
Slc35f2	Solute carrier family 35, member F2	35.13809	0.000397
Myo1b	Myosin IB	6.942870328	0.023473
Tcf7	Transcription factor 7, T cell specific	4.800597937	0.013887
Axin2	Axin 2	4.416998695	0.022697
Pla2g16	Phospholipase A2, group XVI	4.319974957	0.039368
Il17ra	Interleukin 17 receptor A	3.86500417	0.031256
Extl3	Exostoses (multiple)-like 3	3.381491933	0.037503
Ptprg	Protein tyrosine phosphatase, receptor type, G	2.158891183	0.022697
Cachd1	Cache domain containing 1	2.065569075	0.007219

Genes are displayed that were significantly upregulated in Ctnnb1^OE−EC LSEC compared to Ctnnb1^WT LSEC with a fold change (FC) > 2 and also overexpressed in brain endothelial cells compared to liver endothelial cells (Daneman et al., 2010; Sabbagh et al., 2018).