Table 1. Characteristics of patients.
Characteristic | Training cohort | Test cohort | |||||
---|---|---|---|---|---|---|---|
Calciphylaxis (+) | Calciphylaxis (−) | P value | Calciphylaxis (+) | Calciphylaxis (−) | P value | ||
Patients, n | 19 | 41 | 8 | 12 | |||
Age, mean (SD), years | 49.16 (13.45) | 63.20 (15.21) | 0.001 | 66.88 (13.22) | 59.83 (12.64) | 0.30 | |
Sex, No. [%] | 19 [100] | 41 [100] | 0.27 | 8 [100] | 12 [100] | 0.62 | |
Male | 13 [68] | 20 [49] | 7 [88] | 9 [75] | |||
Female | 6 [32] | 21 [51] | 1 [12] | 3 [25] | |||
BMI, mean [SD], kg/m2a | 22.36 [4.10] | 22.86 [3.62] | 0.48 | 23.62 [3.41] | 23.81 [50.02] | 0.90 | |
CKD level, No. [%] | 19 [100] | 41 [100] | 0.30 | 8 [100] | 12 [100] | – | |
4 | 0 [0] | 4 [10] | 0 [0] | 0 [0] | |||
5 | 19 [100] | 37 [90] | 8 [100] | 12 [100] | |||
Current cigarette smoker, No. [%] | 1 [5] | 5 [12] | 0.65 | 2 [25] | 2 [17] | >0.99 | |
Alcohol abuse, No. [%] | 0 [0] | 0 [0] | – | 0 [0] | 0 [0] | – | |
Coronary artery disease, No. [%] | 1 [5] | 8 [20] | 0.25 | 1 [13] | 2 [17] | >0.99 | |
Diabetes, No. [%] | 4 [21] | 21 [51] | 0.03 | 4 [50] | 5 [42] | >0.99 | |
Diabetes mellitus type 1, No. [%] | 1 [5] | 1 [2] | 0 [0] | 0 [0] | |||
Diabetes mellitus type 2, No. [%] | 3 [16] | 20 [49] | 4 [50] | 5 [42] | |||
Hepatobiliary disease, No. [%] | 4 [21] | 4 [10] | 0.25 | 3 [38] | 1 [8] | 0.26 | |
Hypertension, No. [%] | 15 [79] | 37 [90] | 0.25 | 7 [88] | 11 [92] | >0.99 | |
Hyperparathyroidism, No. [%] | 7 [367] | 4 [10] | 0.03 | 3 [38] | 3 [25] | 0.64 |
a3 patients in training cohort with no available BMI data, and 1 patient in test cohort with no available BMI data. BMI, body mass index; CKD, chronic kidney disease; SD, standard deviation.