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. 2021 Sep 29;11:735476. doi: 10.3389/fonc.2021.735476

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Copyright © 2021 Venetis, Fusco and Sajjadi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Oncoprint visualization of molecular alterations in the MMR genes in triple-negative breast cancer. Alterations across all breast cancer subtypes are color-coded on the basis of the legends on the bottom. Each column represents a sample, each row an MMR gene. Somatic MMR mutations (A) are seen in 35 (2%) of queried patients from MSK study with the majority showing missense mutation, while MMR mRNA alterations (B) in n = 363 (19%) from METABRIC study. Tumors included in this analysis have been retrieved from cbioportal.org.