Table 3.

AI/ML based studies on COVID-19 vaccine design

AI/ML tools	Details	Website URL	References
Artificial neural network	Identification of SARS-CoV-2 T-cell and B-cell epitopes based on viral protein antigen presentation and antibody binding properties	NA	[70]
XGBoost	Prediction of vaccine candidates from non-structural proteins	NA	[71]
Feed-forward neural network	Prediction of HLA-binding peptides from SARS-CoV-2 virus by binding stability	NA	[72]
Deep neural network	Prediction and design of multi-epitope vaccine that can manage with the mutation of the virus	https://github.com/zikunyang/DCVST	[73]