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. 2020 Feb 29;22(4):772–788. doi: 10.1093/biostatistics/kxz065

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Published by Oxford University Press 2020. This work is written by US Government employees and is in the public domain in the US.

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Fig. 1. — Power comparison among MTOP, FTOP, standard logistic regression, two-stage model with only complete data and polytomous model with random samples. For the three figures in the first row, four tumor markers were included in the analysis. Three binary tumor marker and one ordinal tumor marker defined 24 cancer subtypes. Around cases would be incomplete. For the three figures in the second row, two extra binary tumor markers were included in the analysis. The six tumor markers defined 96 subtypes. Around cases would be incomplete. The power was estimated by controlling the type I error .

Inline graphic — Power comparison among MTOP, FTOP, standard logistic regression, two-stage model with only complete data and polytomous model with random samples. For the three figures in the first row, four tumor markers were included in the analysis. Three binary tumor marker and one ordinal tumor marker defined 24 cancer subtypes. Around cases would be incomplete. For the three figures in the second row, two extra binary tumor markers were included in the analysis. The six tumor markers defined 96 subtypes. Around cases would be incomplete. The power was estimated by controlling the type I error .