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. 2021 Sep 30;26(19):5931. doi: 10.3390/molecules26195931

Figure 7.

Figure 7

Effect of 6-shogaol on tubular cell necroptosis in cisplatin-treated mice. (A) Western blotting of receptor-interacting serine/threonine protein kinase 1 (RIPK1), RIPK3, mixed-lineage kinase domain-like protein (MLKL), and p-MLKL. (B) Quantification of western blots for RIPK1, RIPK3, and p-MLKL. GAPDH was used as an internal control. (C) Representative images of IHC staining for RIPK3. Scale bar = 40 μm. (D) Quantification of positive staining for RIPK3. n = 8 per group of mice. * p < 0.05 versus Con. # p < 0.05 versus CP.