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Effect of 6-shogaol on production of cytokines and chemokines in cisplatin-treated mice. (A) Serum levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6). (B) Relative mRNA levels of TNF-α, IL-6, monocyte chemoattractant protein-1 (MCP-1), and C-C motif chemokine ligand 5 (CCL5). GAPDH was chosen as an internal control. n = 8 per group of mice. * p < 0.05 versus Con. # p < 0.05 versus CP.
