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. 2021 Sep 29;26(19):5905. doi: 10.3390/molecules26195905
Abbreviation Full form
API Active Pharmaceutical Ingredient
FDA Food and Drug Administration
BCS Biopharmaceutics Classification System
BBB Blood Brain Barrier
IVIVC In vitro In vivo Co-relationship
CYP450 Cytochrome P450
t1/2 Biological half-life
TI Therapeutic Index
TW Therapeutic Window
MEC Minimum effective concentration
PK Pharmacokinetics
ED50 Effective dose in 50% of subjects
TD50 Toxic dose in 50% of subjects
DDS Drug delivery systems
CRDDS Controlled release drug delivery systems
EPR Enhanced permeability and retention
PLK 1 Serine/threonine-protein kinase
siRNA Small interfering Ribose Nucleic acid
CNTs Carbon nanotubes
SWCNTs Single-walled carbon nanotubes
MWCNTs Multiwalled carbon nanotubes
MMP Matrix metallo proteinases
LCST Lower critical solution temperature
MIP Molecularly Imprinted Polymers
CRISPR Cas9 Clustered regularly interspaced short palindromic repeats
sgRNA Single guide RNA
LOC Lab-on-a-chip
QD Quantun dots
RES Reticulo Endothelial system