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. 2021 Oct 7;26(19):6057. doi: 10.3390/molecules26196057

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© 2021 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Scheme 4 — Resonance of penicillin and reaction with penicillin-binding peptide to acylate the penicillin-binding peptide (37) followed by hydrolysis [45,47,48].