Table 3.
Maximum or minimum values of the main biomarkers during the trial
| PRO group (n = 99) | CON group (n = 101) | p | |
|---|---|---|---|
| The maximum value during the trial | |||
| Lung lesion volume, % | 50 [50–75] | 50 [50–75] | 0.531 |
| C-reactive protein, mg/L | 83 [53–125] | 74 [45–128] | 0.398 |
| White blood cells, 109/L | 8.9 [7.5–12.0] | 10.0 [7.3–14.2] | 0.268 |
| Neutrophils, 109/L | 7.0 [5.3–10.0] | 7.6 [5.0–11.6] | 0.500 |
| ESR, mm/L | 28 [24–32] | 27 [22–30] | 0.132 |
| Creatinine, μmol/L | 96 [83–110] | 99 [84–112] | 0.509 |
| ALT, U/L | 38 [23–85] | 43 [33–74] | 0.964 |
| AST, U/L | 43 [30–59] | 44 [29–58] | 0.396 |
| Total bilirubin, mmol/l | 10 [7–12] | 11 [9–14] | 0.313 |
| LDH, U/L | 652 [542–793] | 633 [464–830] | 0.394 |
| Ferritin, μg/L | 489 [321–762] | 518 [212–988] | 0.753 |
| Fibrinogen, g/L | 6.3 [5.4–7.6] | 6.3 [4.9–7.7] | 0.504 |
| The minimum value during the trial | |||
| Albumin, g/L | 37 [31–42] | 34 [30–37] | 0.057 |
| Lymphocytes, 109/L | 0.7 [0.6–1.1] | 0.9 [0.5–1.2] | 0.189 |
ESR erythrocyte sedimentation rate, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase