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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 May 29;1866(9):158983. doi: 10.1016/j.bbalip.2021.158983

Fig. 7. Effects of myriocin treatment on cell cycle progression and metabolites related to sphingolipids.

Fig. 7.

WT and swi4Δ cells were pre-grown in YPD to stationary phase (24 hours) and seeded in SD medium in the absence or presence of 1 μg. mL−1 of myriocin for five hours at 30 °C. (A) G2/M arrest caused by myriocin treatment in both WT and swi4Δ. Cells were then analyzed by FACS * p<0. 05. N=3. (B-I) Changes in the sphingolipid levels after myriocin treatment. HPLC-MS/MS lipidomic analysis. Data were normalized by phosphate levels (pi). Gray bars indicate WT cells and red bars swi4Δ strain. * p<0. 05. N=2.