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. 2021 Oct 8;26(19):6079. doi: 10.3390/molecules26196079

Figure 2.

Figure 2

Effect of rubiscolins on MOR, DOR, and KOR, observed using the CellKeyTM system. The cells expressing MOR (A), DOR (B), and KOR (C) were treated with each compound (10−11–10−5 M), and changes in impedance (ΔZiec) were measured using the CellKeyTM system. Concentration–response curves were prepared by calculating ΔZiec relative to the data obtained for each positive control: 10−5 M DAMGO for MOR (A), 10−5 M SNC-80 for DOR (B), and 10−5 M U-50488H for KOR (C). All data points are presented as means ± S.E.M. for three independent experiments (n = 3–5).