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. 2021 Oct 13;14:246. doi: 10.1186/s12920-021-01097-5

Table 1.

Descriptive table of demographic variables

Control* Case** p-value
Agea
  < 45 229 (45.8%) 86 (20.5%)  < 0.001
     ≥ 45 271 (54.2%) 333 (79.5%)
Sex
 Female 261 (52.2%) 200 (47.7%) 0.2
 Male 239 (47.8%) 219 (52.3%)
Addictionb
 No 387 (77.4%) 353 (84.2%) 0.0115
 Yes 113 (22.6%) 66 (15.8%)
Tumor location
 Colon 206 (49.2%)
 Rectosigmoid 213 (50.8%)

*Number of controls: 500; **number of cases: 419; Chi-squared test was used to determine the p-value; aa cut off of 45 years old was determined for age according to American Cancer Society Guidelines and US Preventive Services Task Force Recommendation Statement [19, 20]; btype of addiction = smoking (cigarette, hookah, opium)