Table 4.
Model | Genotype | Control (%) | Case (%) | OR (CI95%) | P-value | ORa (CI95%) | P-valuea |
---|---|---|---|---|---|---|---|
Codominant | C/C | 305 (61%) | 215 (51.3%) | Ref | Ref | ||
C/T | 161 (32.2%) | 112 (26.7%) | 0.99 (0.73–1.33) | 0.931 | 0.95 (0.70–1.29) | 0.74361 | |
T/T | 34 (6.8%) | 92 (22%) | 3.84 (2.50–5.90) | 9.01e−10 | 3.68 (2.35–5.75) | 1.20e−08 | |
Dominant | C/C | 305 (61%) | 215 (51.3%) | Ref | Ref | ||
C/T–T/T | 195 (39%) | 204 (48.7%) | 1.48 (1.14–1.93) | 0.00322 | 1.42 (1.08–1.87) | 0.0114 | |
Recessive | C/C–C/T | 466 (93.2%) | 327 (78%) | Ref | Ref | ||
T/T | 34 (6.8%) | 92 (22%) | 3.86 (2.54–5.86) | 2.48e−10 | 3.74 (2.42–5.78) | 2.72e−09 | |
Over dominant | C/C–T/T | 339 (67.8%) | 307 (73.3%) | Ref | Ref | ||
C/T | 161 (32.2%) | 112 (26.7%) | 0.77 (0.58–1.02) | 0.071 | 0.74 (0.55–1.00) | 0.0528 | |
log-Additive | 0, 1, 2 | 500 (54.4%) | 419 (45.6%) | 1.62 (1.35–1.95) | 1.842e−07 | 1.58 (1.30–1.91) | 2.353e−06 |
Bold indicates a p-value less than 0.05 is statistically significant
aAdjusted for age, sex, and addiction