Table 7.
The associations of the genotype within clinical characteristics
| Clinical feature | Characteristic | Genotype | Control | Case | OR (95% CI) | P-value |
|---|---|---|---|---|---|---|
| Sex | Female | C/C | 155 | 95 | Ref | |
| C/T | 89 | 54 | 0.99 (0.65–1.5) | 0.962720 | ||
| T/T | 17 | 51 | 4.89 (2.67–8.97) | 2.72e−07 | ||
| Male | C/C | 150 | 120 | Ref | ||
| C/T | 72 | 58 | 1.01 (0.66–1.53) | 0.97430 | ||
| T/T | 17 | 41 | 3.01 (1.63–5.57) | 0.00043 | ||
| Age | < 45 | C/C | 142 | 50 | Ref | |
| C/T | 71 | 23 | 0.92 (0.52–1.63) | 0.7744 | ||
| T/T | 16 | 13 | 2.31 (1.04–5.13) | 0.0404 | ||
| ≥ 45 | C/C | 163 | 165 | Ref | ||
| C/T | 90 | 89 | 0.98 (0.68–1.41) | 0.900 | ||
| T/T | 18 | 79 | 4.34 (2.49–7.56) | 2.30e−07 | ||
| Addictiona | No | C/C | 234 | 180 | Ref | |
| C/T | 131 | 95 | 0.94 (0.68–1.31) | 0.72454 | ||
| T/T | 22 | 78 | 4.61 (2.76–7.69) | 4.76e−09 | ||
| Yes | C/C | 71 | 35 | Ref | ||
| C/T | 30 | 17 | 1.15 (0.56–2.36) | 0.704302 | ||
| T/T | 12 | 14 | 2.37 (0.99–5.65) | 0.052515 |
Bold indicates a p-value less than 0.05 is statistically significant
aType of addiction = smoking (cigarette, hookah, opium)