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. 2021 Oct 13;10:146. doi: 10.1186/s13756-021-01016-4

Table 2.

Cost attributable to SSI-CRAN

Study period 2013–17 (n = 1017)
No SSI-CRAN (n = 911) SSI-CRAN (n = 106)
Superficial incisional (n = 10) Deep incisional (n = 19) Organ-space (n = 77) Total (n = 106)
1-year hospital stay
Mean days ± SE 16.5 ± 23.5 31.8 ± 40.6 27.1 ± 28.7 48.1 ± 29.5 42.8 ± 31.5
Mean cost (€) ± SE 8,030.4 ± 346.5 14,827.9 ± 5,710.8 12,740.7 ± 2,930.4 22,088.1 ± 1.494.2 19,727.7 ± 1,358.3
95% CI 7,350.3– 8,710.4 1,909.3–27,746.7 6,584.2–18,897.2 19,112.1–25,063.9 17,034.5–22,420.9
Sub-total cost (€) 6,687,078 141,379.62 228,963.85 1,647,650.54 2,017,994
Cost of re-intervention (€)
Number of cases, n (%) 3 (30) 10 (52.6) 72 (93.5) 85 (80.2)
Mean re-intervention per patient ± SE 0.5 ± 0.3 0.6 ± 0.2 1.7 ± 0.1 1.4 ± 0.1
Mean cost ± SE 414 ± 234.5 508.4 ± 138 1182.9 ± 79.5 989.4 ± 72.8
95% CI 116.6–944.6 218.4–798.4 1,024–1,341.2 845–1133.8
Sub-total cost (€) 3600 8400 79,200 91,200
Cost of implant (€)
Number of cases, n (%) 1 (10) 1 (5.2) 28 (36.4) 30 (28.3)
Mean cost ± SE 2712 ± 514.5 2163 ± 405.4
95% CI 1687.4–3736.6 1359.2–2966.8
Sub-total cost (€) 10,820 9635.5 208,826.8 229,282.42
Cost of antibiotic treatment (€)
Number of cases, n (%) 5 (50) 13 (68.4) 71 (92.2) 89 (83.9)
Mean cost ± SE 1097.8 ± 728.29 804.6 ± 258.7 1540.2 ± 207.1 1366.6 ± 172.37
95% CI 549.7–2745.3 261.1–1348.2 1127.7–1952.7 1024.8–1708.4
Sub-total cost (€) 10,977.7 15,287.7 118,594.4 144,859.8
Total cost (€)
Number of cases 911 10 19 77 106
Mean cost ± SE 8,030.8 ± 346.5 17,424.8 ± 6,686.7 14,560.9 ± 3,564.1 27,525 ± 1,611.7 24,248.5 ± 1,547.2
95% CI 7350.6–8710.9 2298.5–32,551.2 7073.1–22,048.7 24,315.2–30,735.1 21,180.6–27,316.4
Total cost 7,315,668 172,567.3 276,207.1 2,116,941 2,568,716.1

CI confidence interval, SE standard error, SSI-CRAN surgical site infection after craniotomy