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. 2021 Oct 13;10:146. doi: 10.1186/s13756-021-01016-4

Table 4.

Mean cost of preventive measures between periods per year and mean cost of SSI-CRAN between periods per year

Cost/unit (€) Cost/craniotomy (€) Cost/year (€)
Mean cost of preventive measures between periods
 Pre-care bundle perioda
  Systemic antibiotic prophylaxis:   Cefuroxime 1.5 g 2.6 5.2 1029.6
  Sterile impermeable drape 0.3 0.3 59.4
  Total cost 2.9 5.5 1089
 Care bundle perioda
  Systemic antibiotic prophylaxis: cefuroxime 1.5 g 2.6 5.2 1097.2
  Topical antibiotic prophylaxis: vancomycin 1 g 6.9 6.9 1455.9
  Sterile absorbent drape 0.6 2.6 548.6
  Total cost 10.1 14.7 3101.7
SSI-CRAN cost/year Measures cost/year Total cost
Mean cost of SSI-CRAN between periods
Pre-care bundle period 714,886 1089 715,975
Care bundle period 212,029 3101.7 215,130.7
Difference of cost between periods 500,844.3

aCommon costs between periods are not included (ex: antiseptic soap)