Table 3.
Univariate analysis of prognostic factors associated with LPFS in patients with ESCC treated with chemoradiotherapy
Variables | Training cohort p | Validation cohort p | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Age | 0.987 | 0.967–1.007 | 0.202 | 0.984 | 0.957–1.011 | 0.252 |
Gender | 1.639 | 1.014–2.650 | 0.044 | 1.198 | 0.652–2.202 | 0.560 |
Tumor location | 1.120 | 0.851–1.473 | 0.419 | 1.289 | 0.917–1.812 | 0.143 |
T stage | 2.015 | 1.453–2.793 | < 0.001 | 1.943 | 1.227–3.077 | 0.005 |
N stage | 1.867 | 1.446–2.410 | < 0.001 | 1.765 | 1.215–2.563 | 0.003 |
Clinical stage | 2.194 | 1.581–3.044 | < 0.001 | 2.309 | 1.440–3.704 | 0.001 |
Radiation dose | 0.965 | 0.923–1.009 | 0.118 | 0.996 | 0.921–1.078 | 0.927 |
LDH | 1.641 | 1.116–2.414 | 0.012 | 1.369 | 0.778–2.408 | 0.276 |
NLR | 1.069 | 0.965–1.184 | 0.199 | 1.015 | 0.901–1.142 | 0.810 |
PLR | 1.001 | 0.999–1.003 | 0.177 | 1.001 | 0.999–1.004 | 0.377 |
CR status | 0.128 | 0.072–0.228 | < 0.001 | 0.295 | 0.157–0.556 | < 0.001 |