Fig. 1.

Enterovirus type identification in HFMDs individual by NGS. A Individuals distribution of the samples with enterovirus type. Red box highlight the co-infection samples. Asterisk means statistical significance difference between mild and severe cases number for enterovirus (Fisher’s exact test p < 0.05). EV71: Human Enterovirus 71; start with “A”: Coxsackievirus A. start with “B”: Coxsackievirus B; start with “EC”: ECHO-virus. B Main virus amount by NGS compare between severe and mild cases. RPM: reads number per million sequenced reads. NS not significant