Fig. 4.

Effects of TC-G 1008 treatment on neurological function and brain atrophy at 4 weeks post-HIE. TC-G 1008 treatment group showed significant improvement in spatial memory loss as shown by shorter swimming distance (A), decrease in escape latency (B), and more time spent in the target quadrant during the probe trial (C, D).TC-G 1008 treatment significantly improved motor function as shown by foot-fault test (F) and rotarod test (G).TC-G 1008 treatment significantly reduced the percent of tissue loss (E, H) when compared with the vehicle