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. 2021 Oct 13;21:244. doi: 10.1186/s12871-021-01387-6

Fig. 1.

Fig. 1

Study diagram. Legend: This diagram follows STARD reporting guideline for diagnostic accuracy studies. CS-AKI: cardiac surgery-associated acute kidney injury; CPB: cardiopulmonary bypass; pCr: plasma creatinine; TIMP2 IGFBP7: tissue inhibitor of metalloproteinase 2 – insulin-like growth factor-binding protein 7; RRT: renal replacement therapy. CS-AKI was classified according to Kidney Disease Improving Global Outcome (KDIGO) guidelines including both pCr change and the urine output criterion