Table 1.
Patients’ characteristics
|
CS-AKI n=27 (42 %) patients |
No CS-AKI n=38 (58 %) patients |
p | |
|---|---|---|---|
| Age (years) | 78 [75-86] | 79 [75-86] | 0.14 |
| Female gender (n [%]) | 12 (44 %) | 21 (55 %) | 0.39 |
| Body mass index (kg/m2) | 27 [25-30] | 26 [23-27] | 0.04 |
| Weight (kg) | 75 [67-83] | 69 [59-79] | 0.06 |
| EuroSCORE II (%) | 3.4 [2.0-5.5] | 1.8 [1.4-3.5] | 0.016 |
| SAPS II | 27 [24-32] | 24 [22-27] | 0.006 |
| Comorbidities | |||
| Hypertension (n [%]) | 17 (63 %) | 28 (76 %) | 0.27 |
| Diabetes mellitus (n [%]) | 5 (19 %) | 9 (23 %) | 0.58 |
| COPD (n [%]) | 2 (7 %) | 1 (3 %) | 0.38 |
| History of heart surgery (n [%]) | 1 (4 %) | 1 (3 %) | 0.82 |
| Preoperative LV ejection fraction <35 % (n [%]) | 1 (4 %) | 0 (0 %) | 0.24 |
| History of peripheral vascular surgery (n [%]) | 3 (11 %) | 2 (5 %) | 0.40 |
| Preoperative serum creatinine (μmol/L) | 82 [74-91] | 79 [66-92] | 0.34 |
| Preoperative eGFR (mL/minute/1.73 m2) | 75 [54-83] | 70 [64-81] | 0.85 |
| eGFR before CPB <60 mL/min/1.73 m2 | 7 (26 %) | 5 (13 %) | 0.38 |
| Cross-clamp time (minutes) | 45 [38-58] | 56 [43-68] | 0.014 |
| CPB time (minutes) | 61 [53-76] | 68 [56-89] | 0.09 |
| CPB priming (mL) | 1000 [1000-1100] | 1000 [1000-1025] | 0.79 |
| Volume expansion (mL) | |||
| Intraoperative | 850 [500-1100] | 600 [500-1000] | 0.33 |
| Post-operative (24h) | 750 [500-1250] | 500 [250-875] | 0.046 |
| Intraoperative transfusion | |||
| Red blood cell autotransfusion (mL) | 400 [210-500] | 400 [300-500] | 0.85 |
| Packed red blood cell (n patients) | 6 (22 %) | 13 (35 %) | 0.35 |
| Packed red blood cell >2 packs (n patients) | 1 (4 %) | 0 (0 %) | 0.24 |
| Fresh frozen plasma (n patients) | 1 (4 %) | 0 (0 %) | 0.24 |
| Platelet transfusion (n patients) | 1 (3 %) | 1 (4 %) | 0.82 |
| Postoperative (48h) transfusion | |||
| Packed red blood cell (n patients) | 6 (22 %) | 4 (11 %) | 0.22 |
| Packed red blood cell > 2 packs (n patients) | 1 (4%) | 0 (0 %) | 0.24 |
| Fresh frozen plasma (n patients) | 1 (4 %) | 1 (3 %) | 0.82 |
| Platelet transfusion (n patients) | 1 (4 %) | 0 (0 %) | 0.24 |
| Post-operative (24 h) urine output (mL/kg/h) | 0.7 [0.5-0.9] | 1.0 [0.7-1.3] | 0.003 |
| Diuretics within 24 postoperative hours (n [%]) | 19 (70 %) | 14 (38 %) | 0.010 |
| Vancomycin for antibioprophylaxis (n [%]) | 0 (0 %) | 0 (0 %) | - |
| Aminoglycosides within 48 postop. hours (n [%]) | 0 (0 %) | 1 (3 %) | 0.39 |
| Re-operation within 48 hours | 2 (7 %) | 0 (0 %) | 0.10 |
| ICU length of stay (days) | 3 [2-5] | 2 [1-3] | 0.037 |
| Hospital length of stay after the surgery (days) | 10 [8-14] | 9 [8-13] | 0.37 |
| Hospital mortality (n [%]) | 0 (0 %) | 1 (3 %) | 0.39 |
eGFR estimated glomerular filtration rate (modification of diet in renal disease equation), COPD Chronic obstructive pulmonary disease, ICU intensive care unit, SAPS II simplified acute physiology score 2, LV left ventricle, CPB cardiopulmonary bypass
Results are expressed as n (%) or median [interquartile range]