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. Author manuscript; available in PMC: 2021 Oct 13.
Published in final edited form as: Cell Host Microbe. 2009 Oct 22;6(4):292–294. doi: 10.1016/j.chom.2009.09.008

Figure 2. Neutralization of HIV-1 at a V2-V3 epitope.

Figure 2.

Recognition of trimeric HIV-1 Env by PG antibodies (green) requires both a V2-V3 epitope and an associated glycan, whereas the previously defined strain-specific 2909 antibody (blue) requires a V2-V3 epitope and a lysine. (The HIV-1 Env is shown with subunits in red, purple and yellow; gp41 is represented by the small ball at the center of the spike and gp120 as a larger oval with arms labeled V2 and V3.)