Table 5.
Some progress of electrospinning in drug delivery in recent years
| Material | Solvent | Flow rate (mL/h) | Distance (cm) | Voltage (kV) | Type | Drug | Reference |
|---|---|---|---|---|---|---|---|
| Cellulose acetate/gliadin | HFIP/TFA | 0.1–0.5 | 20 | 15 | Coaxial | Ferulic acid | [396] |
| Hydroxypropyl-beta-cyclodextrin | Water | 0.5 | 15 | 15 | Blend | Ibuprofen | [397] |
| PLA/PVP/multiwall carbon nanotubes | DMF/THF | 0.3–1 | 22.5 | 15 | Blend | Tetracycline hydrochloride | [398] |
| PCL/PEO | DCM/DMF | 0.1–0.6 | 10–15 | 12/15 | Blend | Doxycycline | [399] |
| poly(glycolide-ε-caprolactone)/PLGA | DCM | 2 | 15 | 20 | Blend | papaverine hydrochloride | [400] |
| Poly(N-isopropylacrylamide)/Eudragit L100-55 | Ethanol | 1 | 20 | 16 | Blend | Ketoprofen | [401] |
| Carboxylated cellulose nanocrystals/cellulose acetate | acetone/DMAc | 1 | 15 | 25 | Blend | Tetracycline hydrochloride | [402] |
| PLA/PCL | DCM/DMF | 2 | 15 | 20/25 | Blend | Bovine serum albumin | [403] |
| PCL | Chloroform/methanol | 2 | 15 | 10 | Blend | Cilostazol | [404] |
| Silk fibroin/gelatin | Formic acid | 0.3 | 10 | 20 | Blend | Thyme essential oil/doxycycline monohydrate | [405] |
| Sodium carboxymethyl cellulose/methyl acrylate/PEO | DMF/chloroform/methanol | 3 | 18 | 18 | Coaxial | Tetracycline hydrochloride | [406] |
| PVA/chitosan/functionalized graphene oxide | Acetic acid | 0.6 | 14 | 22 | Blend | Curcumin | [407] |
| Ethyl hydroxy ethyl cellulose or hydrophobically modified ethyl hydroxy ethyl cellulose/PVA/citric acid | THF | 0.2 | 15 | 27 | Blend | Chlorhexidine Digluconate | [408] |
| PLA/PVA | DMF/chloroform | 1.5 | 9 | 15 | Blend | Dexamethasone | [409] |
| Sodium carboxymethyl cellulose/PEO/methyl acrylate | DMF/chloroform/methanol | 3/0.4 | 18 | 15 | Coaxial/Blend | Tetracycline hydrochloride | [406] |
| PCL-PEG-PCL | DCM/hexane | 6 | 12 | 18 | Blend | Magnetic iron oxide nanoparticles | [410] |
|
Poly(3- hydroxybutyrate-co-3-hydroxyvalerate)/cellulose nanocrystals |
DMF/chloroform/acetone | 1 | 18 | 15 | Blend | Tetracycline hydrochloride | [411] |
| PVA/montmorillonite | Acetic acid | 1–10 | 10–25 | 10–25 | Blend | Bovine serum albumin | [412] |
| Zein | Ethanol | 0.12 | 12 | 24 | Blend | Progesterone | [413] |
| Glutinous rice starch/PVA | Water | 0.3 | 15 | 18–20 | Blend | Chlorpheniramine maleate | [414] |
| PEG/PLGA/Au@Fe2O3 nanoparticles | DMF/DCM | 1 | 15 | 30 | Coaxial | Silibinin | [415] |
| PLLA | HFIP | 0.6 | 12 | 15 | Blend | Lovastatin | [416] |
| TPU | DMF | 1 | 20 | 13 | Blend | Naproxen | [417] |
| PCL/gum tragacanth | Acetic acid | 1 | 15 | 15 | Blend | Curcumin | [418] |
| Chitosan/phospholipids | TFA/DCM | 1.2 | 10 | 25 | Blend | Vitamin B12/curcumin/diclofenac | [419] |
| PCL | Chloroform/methanol | 0.5/0.6 | 9 | 12 | Coaxial | Ampicillin | [420] |
| PU/hydroxypropyl cellulose | DMF | 1 | 15 | 15 | Blend | Donepezil | [421] |
| PVA/collagen | Acetic acid | 0.4 | 15 | 18 | Blend | Salicylic acid | [422] |
| PVA/sodium alginate | Water | 0.3 | 10 | 14 | Blend | Moxifloxacin hydrochloride | [423] |
| Gelatin | Acetic acid | 0.3 | 10 | 12 | Blend | Piperine | [424] |