TABLE 2.

Chronological change values of the dysphonic parameters

					(Mean ± SE)
		2w	4w	8w	12w
Aberrant morae	BT	−9.9 ± 2.66 b	−7.0 ± 2.30 a	−6.3 ± 1.90 a	−3.5 ± 1.42 a
	Placebo	−1.1 ± 0.68	−0.2 ± 0.46	−0.3 ± 0.62	0.4 ± 0.43
(S) in GRBAS	BT	−1.18 ± 0.33 b	−0.91 ± 0.37 a	−0.73 ± 0.36 a	−0.36 ± 0.24
	Placebo	−0.18 ± 0.18	−0.27 ± 0.36	−0.00 ± 0.19	−0.27 ± 0.30
VHI	BT	−14.6 ± 7.35	−24.0 ± 9.63 a	−20.6 ± 9.91 a	−16.7 ± 7.59 a
	Placebo	−9.8 ± 3.32	−5.3 ± 3.43	−8.0 ± 3.52	−5.7 ± 4.90
VAS	BT	−11.6 ± 8.67	−20.5 ± 8.74	−18.6 ± 10.53	−15.6 ± 8.68
	Placebo	−2.0 ± 4.09	−6.2 ± 4.67	−0.2 ± 4.70	−3.2 ± 3.95

Abbreviations: BT, botulinum toxin; VHI, Voice Handicap Index; VAS, visual analogue scale.

^a <0.05 (vs baseline).

^b <0.01 (vs baseline).