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. 2021 Oct 13;95(21):e01246-21. doi: 10.1128/JVI.01246-21

FIG 11.

FIG 11

Dynapyrazole-A or DIC knockdown prevents the assembly of DLPs from viroplasms. (A) MA-104 cells were infected with RVA-NMTL (MOI = 0.1) and then treated with 3 μg/ml dynapyrazole-A or DMSO and RVA-NMTL-neutralizing hyperimmune serum starting at 1.5 hpi. (B) MA-104 cells were transfected with siDIC or siCON for 36 h and then infected with RVA-NMTL (MOI = 0.1). In panels A and B, TEM was used to analyze the cells at 12 hpi. “V” represents viroplasms. Arrows show DLPs assembled from viroplasms. Black boxes show magnified images.